Supplier of Polyethylene Glycol 6000 (PEG-6000) From Turkey and Dubai-UAE

Polyethylene Glycol 6000(PEG-6000)

Polyethylene Glycol 6000 (PEG-6000) is a polymer of ethylene oxide, a type of polyethylene glycol (PEG) with an average molecular weight of 6000 g/mol. PEGs are available in various molecular weights, with PEG-6000 being one of the higher molecular weight varieties.

Applications of Polyethylene Glycol 6000

1. Pharmaceuticals: Used as a base for ointments, creams, and as a solvent or stabilizer in drug formulations.
2. Cosmetics: Functions as a humectant, lubricant, and thickener in skincare products.
3. Industrial Uses: Serves as a lubricant, dispersing agent, and in the production of plastic films and sheets.
4. Biotechnology: Employed in processes like protein purification and in cryopreservation.

Properties of PEG-6000:

• Molecular Formula: H(OCH₂CH₂)nOH
• Molecular Weight: Approximately 6000 g/mol
• Appearance: White, waxy solid or flakes
• Solubility: Soluble in water and various organic solvents (e.g., ethanol, acetone)

Specific Uses of PEG-6000

1. Pharmaceuticals:
   –  Tablet Coating and Binding: PEG-6000 is often used in solid dosage forms like tablets and capsules. It acts as a binder, helping to hold the tablet components together, and as a coating agent to improve the appearance and control the release of the active ingredient.
   –  Drug Solubility and Stability: It can enhance the solubility of poorly water-soluble drugs and stabilize formulations by preventing the crystallization of drug substances.
   –  Suppositories: Due to its solid state at room temperature and ability to melt at body temperature, PEG-6000 is used in the production of suppositories, ensuring proper release of the active ingredients.
2. Cosmetics:
   –  Moisturizers and Lotions: PEG-6000 acts as a humectant, drawing moisture to the skin and enhancing hydration. It’s also used as a thickening agent in lotions, creams, and other skincare products to improve texture and consistency.
   –  Hair Care Products: In shampoos and conditioners, PEG-6000 helps in thickening the product, providing a smoother application, and acting as a conditioning agent.
3. Industrial Uses:
   –  Plastic Production: PEG-6000 is used as a plasticizer in the production of plastics and resins, improving flexibility and workability.
   –  Lubricants: It serves as a lubricant in various mechanical and industrial applications, reducing friction between surfaces and improving the lifespan of machinery parts.
   –  Paints and Coatings: In the manufacturing of paints and varnishes, PEG-6000 is used to control viscosity and improve the spreadability of the product.
4. Biotechnology:
   –  Protein Purification:  PEG-6000 is employed in the purification of proteins through a process called “PEG precipitation,” where it helps in selectively precipitating proteins from solution.
   –  Cryopreservation: It is used as a cryoprotectant to protect biological tissues and cells during freezing, preventing ice crystal formation that can damage cell structure.

Safety Guidelines

1. General Safety:
   – PEG-6000 is generally considered non-toxic and safe for use in pharmaceuticals, cosmetics, and food products.
   – It is non-irritating and non-sensitizing in most cases, though high concentrations or prolonged exposure can lead to skin irritation, particularly in individuals with sensitive skin.
2. Handling and Storage:
   – Store in a cool, dry place away from direct sunlight and moisture to maintain its stability and prevent degradation.
   – Use personal protective equipment (gloves, goggles) when handling large quantities to avoid prolonged skin or eye contact.
3. Environmental Impact:
   – PEG-6000 is biodegradable, and its environmental impact is relatively low. However, proper disposal according to local regulations should be followed to minimize any potential environmental harm.
4. Regulatory Considerations:
   – PEG-6000 is approved for use by various regulatory bodies, including the FDA, for specific applications in food, cosmetics, and pharmaceuticals.
   – It is important to adhere to the concentration limits set by these regulatory authorities to ensure safety and efficacy in its intended use.

Technical Data Sheet PEG-6000